- Work Packages
- WP 1Management & Coordination
- WP 2 (OSD)Ocean Sampling Day
- WP 3Oceanography & Environmental Data
- WP 4Standards and Interoperability
- WP 5Bioinformatics & Data Integration
- WP 6Exploring Ecosystems Biology
- WP 7Function and Biotechnology
- WP 8Intellectual Property (IP) Management for Marine Bioprospecting
- WP 9Dissemination & Outreach
- Public DeliverablesAll Micro B3's public deliverables
- Third Micro B3 Industry Expert Workshop
- Micro B3 Industry Expert Workshop
- Micro B3/OSD Analysis Workshop
- Micro B3 Stakeholder Workshop
- Micro B3 Summer School in Crete 2014
- Marine Metagenomics Bioinformatics
- Micro B3 Industry expert workshop
- EU-US Training 2013
- Micro B3 Statistics Training 2013
- MG4U Bioinformatics Training 2013
- Bioinformatics Training 2012
- EU-US Training 2012
Industry Expert Workshop Programme
Marine Micr'Omics for Biotech Applications
2nd Industry Expert Workshop, a joint dissemination activity
by the MicroB3, MaCuMBA and PharmaSea EU Projects
PharmaMar, Colmenar Viejo, Spain, 30 - 31 March 2015
FINAL PROGRAMME (download PDF)
Monday, 30 March 2015
12.00-13.00 Registration and Finger Food to start Networking
13.00-14.10 Welcome and Introduction (Johanna Wesnigk) 13.00-13.30 Showing 20mins Micro B3 documentary film; logistics 13.30-13.40 Simon Munt on behalf of Pharma Mar: Welcome of the host 13.40-13.50 Frank Oliver Glöckner, Jacobs University Bremen: Short introduction to Micro B3 13.50-14.00 Lucas Stal, NIOZ, NL: Short introduction to MaCuMBA 14.00-14.10 Marcel Jaspars, Univ. Aberdeen: Short introduction to PharmaSea 14:10-16:10 Session 1: Natural products based on marine biodiversity
Chair: Fernando de la Calle, PharmaMar
This session will present real cases of
- the current strategy of drug discovery using marine organisms,
- genomic mining into the universe of microbial biodiversity,
- the designing of unnatural new compounds by genomic manipulation, and
- present & future trends in drug delivery of marine compounds.
15.50-16.10 Simon Munt (PharmaMar): Marine Natural Products: Is the best yet to come?
16:30-19:00 Session 2: Environmental biotechnology through marine microbial knowledge
Chair: Juan Luis Ramos, Bio-iliberis and Abengoa
Molecular biology tools have first been used to understand the biology of a number of microbes cultivated in the laboratory. Then efforts brought this set of techniques to the study and understanding of microbes inhabiting different environments, and a number of reports proved that all niches explored on Earth are inhabited by microbes. Especially metagenomics and metaproteomics techniques are revealing a wealth of unexpected functions while also explaining the adaptation of microbes to extreme environments. A number of the enzymes from oceanic metagenomic libraries are revealing potentially new applications in industry. In this session we intend to explore some of the approaches and how enzymes of industrial interest can be rescued and evolved.
16.30-16.55 Alexander Wentzel (SINTEF, Trondheim): Comparative metagenomics and bioprospecting of deep sub-surface oil reservoirs on the Norwegian continental shelf 16.55-17.20 Manuel Ferrer (CSIC-ICP, Madrid): Re-directing biotech opportunities through metagenomics 17.20-17.45 Jose Miguel Seoane (REPSOL, Madrid): Model-driven multi-scale optimization of microbial cell factories 17.45-18.10 Pablo Pomposiello Miravent (CEO BAcMine, Madrid): Ligand-responsive circuits, synthetic biology and bioprocesses 18.10-18.35 Juan Luis Ramos (Abengoa & Bio-Iliberis): Discovering enzymes of industrial interest from marine metagenomic libraries
18.35-19.00 Discussion on marine and environmental biotechnology
The shuttle bus will leave at 19.15 for Colmenar Cercanias station
21:00 Joint workshop dinner in city restaurant, Madrid
9:00-10:30 Session 3: Bioinformatic tools and methods for innovative blue biotechnology
Chair: Renzo Kottmann, MPI Bremen, Germany
This session will present and discuss new developments in bioinformatics algorithms, tools and standards for the (meta)genomic identification and analysis of unknown genes and biosynthetic gene clusters that are relevant for marine biotechnology. The discussion will focus on what is needed to bring bioinformatics closer to biotechnological applications, by accelerating the industrial utilization of newly developed methods and by filling gaps in the knowledge transfer between academia and industry.
09.00-09.30 Marnix H. Medema (Univ. Wageningen): Computational genomic strategies and standards for natural products discovery and engineering 09.30-10.00 Antonio Fernàndez-Guerra (Univ. Oxford): Computational approaches to biodiscovery in metagenomes 09.50-10.15 Tom van den Bergh (Bio-Prodict, NL): Protein superfamily data integration for protein engineering
10.15-10.30 Discussion on bioinformatics tools for biotechnology
11.00-12:30 Session 4: New strategies for high throughput isolation of novel marine microorganisms
Chair: Lucas Stal, NIOZ, The Netherlands
This session will discuss new strategies for the isolation and cultivation of novel marine microorganisms and the importance and problems of their deposition in accessible culture collections. The session will also discuss the possibility of using ‘omics’ approaches for targeted isolation of specific microorganisms based on their predicted biotechnological applications. We will further discuss issues regarding intellectual property rights of cultures and the consequences of the implementation of the Nagoya protocol by the European Union.
11.00-11.25 Jörg Overmann, (DSMZ, Braunschweig): Accessing and securing novel marine microbial resources through cultivation 11.25-11.45 Colin Ingham, (MicroDish, Utrecht): Microengineered chips based around porous aluminium oxide for microbial cultivation 11.45-12.05 Helena Vieira (Marine Biotech Expert, University of Lisbon): Discovering the unknown -how to drive research for marketable biotechnological applications of novel marine microorganisms 12.05-12.30 Caroline von Kries (Environmental Law, Univ. Bremen): Points to consider for ABS Agreements based on the Micro B3 Model Agreement
13:30-15:00 Panel Discussion: Bioactives of marine origin – opportunities and
Chair: Marcel Jaspars, co-moderator Johanna Wesnigk
A panel formed by participants from industry and EU project partners will discuss opportunities and challenges in the use of bioinformatics and genomics tools for discovering new marine bioactives relevant for pharmaceutical and other biotechnological applications.
Please note that panelists will be selected from the persons named above and the participants to ensure wide-ranging input.
15.00 Closure of the workshop (F. de la Calle and J. Wesnigk)
t.b.d. Earlier transfer to Colmenar Cercanias station and shared taxis to airport can be arranged, if necessary.
15.15 Final shuttle bus to Colmenar Cercanias station